Abstract Introduction While no direct comparative data exist for crizotinib in ROS1+ non-small cell lung cancer (NSCLC), studies have suggested clinical benefit with this targeted agent.The objective of this study was to assess the cost-effectiveness of crizotinib compared to standard platinum-doublet chemotherapy for first-line treatment of ROS1+
More than 20.000 plant species are used in various traditional medicines around the world, and are considered as potential reservoirs for discovery of new drugs.One of these plants is Melissa officinalis L., commonly known as lemon balm, belongs to the family of Lamiaceae.For more than 2000 years, fragrant leaves of this plant have been widely used
Background: Evidence-based Dresser and Mirror interventions for autism spectrum disorders evaluated in high-income countries typically require highly specialised manpower, which is a scarce resource in most low- and middle-income settings.This resource limitation results in most children not having access to evidence-based interventions.Objective:
Many reports highlight biological responses of crop plants after non-ionizing electromagnetic radiation (EMR) exposure based on the phenotypic and physiological levels.So, this study aimed to estimate genetic alterations in proteins, isozymes, and DNA banding patterns as well as the extent of nuclear DNA damage of economic corn (Zea mays) under the
Background: Members of editorial boards of academic journals are often considered gatekeepers of knowledge and role models for the academic community.Editorial boards should be sufficiently diverse in the background of their members to facilitate publishing manuscripts representing a wide range of research paradigms, methods, and Miscellaneous Acce